Table 2. Univariate and multivariate analysis of prognostic factors for 2-yr disease-free survival.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Age (< 55 yr/ ≥ 55 yr) | 1.11 | 0.77-1.59 | 0.574 | |||
| Gender (male/female) | 1.44 | 0.96-2.14 | 0.077 | |||
| Edmondson grade (I, II vs. III, IV) | 1.75 | 1.13-2.70 | 0.012 | |||
| HBV (absent vs. present) | 1.33 | 0.91-1.95 | 0.145 | |||
| HCV (absent vs. present) | 1.46 | 0.84-2.56 | 0.181 | |||
| AFP level (< 100 ng/mL vs. ≥ 100 ng/mL) | 1.91 | 1.33-2.74 | 0.000 | |||
| Tumor size (≤ 5 cm vs. > 5 cm) | 2.37 | 1.64-3.44 | 0.000 | |||
| Tumor stage (I, II vs. III, IV) | 4.38 | 3.02-6.34 | 0.000 | 2.26 | 1.17-4.36 | 0.01 |
| Vascular invasion (absent vs. present) | 3.83 | 2.37-6.20 | 0.000 | 2.27 | 1.33-3.87 | 0.01 |
| Tumor number (single vs. multi) | 3.06 | 2.12-4.43 | 0.000 | |||
| AROS (low vs. high) | 1.95 | 1.34-2.83 | 0.001 | 1.42 | 0.95-2.12 | 0.08 |
HBV, hepatitis B; HCV, hepatitis C; AFP, alpha fetoprotein.