Table S2. Comparison of clinicopathological information between cirrhotic HCC and non-cirrhotic HCC.
| Clinicopathologic parameters | Cirrhotic HCC (n = 249) | Non-cirrhotic HCC (n = 283) | P value |
|---|---|---|---|
| Age (< 55 / ≥ 55 yr) | 150/99 | 155/128 | 0.236 |
| Gender (Male/Female) | 198/51 | 219/64 | 0.624 |
| Hepatitis B infection (n, %) | 221 (88.9) | 180 (63.6) | < 0.001* |
| Hepatitis C infection (n, %) | 10 (4.0) | 25 (8.8) | 0.042* |
| Tumor stage (I/II/III, IV) | 105/96/48 | 107/113/63 | 0.532 |
| BCLC stage (A/B/C) | 142/75/32 | 128/119/36 | 0.012* |
| AFP level (> 100 ng/mL, %) | 125 (50.2) | 125 (44.1) | 0.205 |
| Microvascular invasion (n, %) | 141 (56.6) | 180 (63.6) | 0.109 |
| Tumor number (multiple, %) | 58 (23.3) | 68 (24.0) | 0.923 |
| Tumor size (≤ 5 / > 5 cm) | 175/74 | 144/139 | < 0.001* |
| Edmondson grade (I/II/III, IV) | 27/169/53 | 25/21/46 | 0.195 |
| Portal Vein Invasion (n, %) | 32 (12.8) | 35 (12.3) | 0.971 |
*Analyzed by chi square test. BCLC, Barcelona Clinic Liver Cancer; AFP, alpha fetoprotein.