Table 3. Multivariate analysis of risk factors for colorectal neoplasia.
| Variables | CRN (-) group (n=3,386) | CRN (+) group (n=1,258) | Multivariate analysis | |
|---|---|---|---|---|
| OR (95% CI) | P value | |||
| Age (yr) | < 0.001 | |||
| <50 | 2,283 | 571 | 1 | |
| ≥ 50 | 1,085 | 687 | 2.53 (2.22-2.89) | |
| Sex | < 0.001 | |||
| Female | 1,366 | 306 | 1 | |
| Male | 2,002 | 952 | 1.97 (1.67-2.33) | |
| Smoking | < 0.001 | |||
| < 20 pack-year | 2,988 | 987 | 1 | |
| ≥ 20 pack-year | 380 | 271 | 1.41 (1.17-1.71) | |
| Alcohol consumption | 0.156 | |||
| < 30 g/day | 2,884 | 1,008 | 1 | |
| ≥ 30 g/day | 484 | 250 | 1.14 (0.95-1.38) | |
| Family history of colorectal cancer | 0.626 | |||
| - | 3,246 | 1,209 | 1 | |
| + | 122 | 49 | 1.08 (0.77-1.51) | |
| Metabolic syndrome | 0.018 | |||
| - | 2,827 | 963 | 1 | |
| + | 541 | 295 | 1.45 (1.13-1.70) | |
| Abdominal obesity | 0.002 | |||
| - | 2,269 | 708 | 1 | |
| + | 1,099 | 550 | 1.26 (1.09-1.45) | |
| Glucose intolerance or type II diabetes | 0.034 | |||
| - | 2,820 | 932 | 1 | |
| + | 548 | 326 | 1.20 (1.01-1.42) | |
| Hypertriglyceridemia | 0.066 | |||
| - | 2,658 | 892 | 1 | |
| + | 710 | 366 | 1.17 (0.99-1.37) | |
| Gallbladder polyp | 0.029 | |||
| - | 3,118 | 1,139 | 1 | |
| + | 250 | 119 | 1.29 (1.03-1.62) | |
| Gallstone | 0.482 | |||
| - | 3,271 | 1,204 | 1 | |
| + | 97 | 54 | 1.14 (0.79-1.63) | |
CRN, colorectal neoplasia; OR, odds ratio; CI, confidence interval.