Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Aug 10;112(34):E4792–E4801. doi: 10.1073/pnas.1423295112

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 5. — The change of SR Ca²⁺ leak and STIM1 overexpression. (A) XY time-series images of [Ca²⁺]_i (fluo 4) in control (Upper) and STIM1 (Lower) overexpressing myocytes. (B) Line scan images of fluo 4 in control and STIM1 overexpressing myocytes (lines are shown in A). (C) An example of Ca²⁺ wave profile (white box in A) in STIM1 overexpressing myocytes. (D) Histogram shows the cell count and Ca²⁺ wave frequency in control and STIM1 overexpressing myocytes. (E) Summary data show the change of Ca²⁺ wave frequency in STIM1 overexpressing myocytes (n = 40 and 58 cells in control and STIM1, respectively). (F) Representative Ca²⁺ wave profiles show the effect of GdCl₃ (1 μM), KB-R 7943 (10 μM), and Tg (2 μM). (G) Summary data show the effect of GdCl₃ and KB-R 7943 on spontaneous Ca²⁺ wave frequency in STIM1 overexpressing myocytes (n = 7 and 5 cells in the Gd³⁺ and KB-R groups, respectively). *P < 0.05 vs. control.