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. 2015 Aug 31;17(1):232. doi: 10.1186/s13075-015-0730-2

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© Markusse et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Total number of flares during year 2 to year 10 in all patients (n = 480), according to the following definitions: Flare A (n = 882/11,458): from any DAS to DAS >2.4 with an increase in DAS ≥0.6; Minor flare B (n = 281/11,458): from DAS ≤2.4 to DAS >2.4 with an increase in DAS <0.6; Major flare B (n = 721/11,458): from DAS ≤2.4 to DAS >2.4 with an increase in DAS ≥0.6. It indicates the concordance and discordance between the definitions of flare. Note, more than one flare according to the same definition or according to another definition can occur in the same patient