Table 2.
Observed deaths and standardised mortality ratios for all causes, all cancers and a priori outcomes by sex and pay code*, Fernald Feed Materials Production Center Cohort, 1951–2004†
| Males (n=5451) | Females (n=952) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hourly (n=3633) | Salaried (n=1818) | Hourly (n=183) | Salaried (n=769) | |||||||||
| Cause‡ | Obs | SMR | 95% CI | Obs | SMR | 95% CI | Obs | SMR | 95% CI | Obs | SMR | 95% CI |
| All causes | 1892 | 0.98 | 0.94 to 1.03 | 678 | 0.77 | 0.71 to 0.83 | 48 | 1.05 | 0.77 to 1.39 | 149 | 0.83 | 0.70 to 0.98 |
| All cancers | 575 | 1.15 | 1.06 to 1.24 | 211 | 0.90 | 0.79 to 1.03 | 13 | 1.05 | 0.56 to 1.79 | 59 | 0.97 | 0.74 to 1.25 |
| MN stomach | 18 | 1.15 | 0.68 to 1.82 | 12 | 1.77 | 0.91 to 3.09 | 0 | 0.00 | 0.00 to 13.2 | 2 | 1.93 | 0.23 to 6.96 |
| MN intestine | 50 | 1.16 | 0.86 to 1.53 | 14 | 0.71 | 0.39 to 1.18 | 2 | 1.66 | 0.20 to 6.00 | 4 | 0.82 | 0.22 to 2.09 |
| MN trachea, bronchus, lung | 223 | 1.25 | 1.09 to 1.42 | 52 | 0.62 | 0.46 to 0.81 | 5 | 2.01 | 0.65 to 4.68 | 17 | 1.13 | 0.66 to 1.81 |
| MN kidney | 12 | 0.95 | 0.49 to 1.66 | 3 | 0.49 | 0.10 to 1.44 | 0 | 0.00 | 0.00 to 18.2 | 3 | 2.99 | 0.62 to 8.75 |
| MN bladder and other urinary organs | 15 | 1.15 | 0.64 to 1.89 | 6 | 1.00 | 0.37 to 2.17 | 0 | 0.00 | 0.00 to 23.7 | 3 | 5.13 | 1.06 to 15.0 |
| Non-Hodgkin’s lymphoma | 18 | 0.97 | 0.58 to 1.54 | 12 | 1.33 | 0.69 to 2.32 | 2 | 4.41 | 0.53 to 16.0 | 0 | 0.00 | 0.00 to 1.71 |
| Hodgkin’s disease | 5 | 1.81 | 0.59 to 4.22 | 1 | 0.76 | 0.02 to 4.23 | 0 | 0.00 | 0.00 to 70.1 | 0 | 0.00 | 0.00 to 13.0 |
| Leukaemia | 17 | 0.92 | 0.54 to 1.48 | 15 | 1.71 | 0.95 to 2.81 | 0 | 0.00 | 0.00 to 9.23 | 3 | 1.61 | 0.33 to 4.70 |
| Multiple myeloma | 12 | 1.44 | 0.75 to 2.52 | 7 | 1.82 | 0.73 to 3.75 | 0 | 0.00 | 0.00 to 17.7 | 0 | 0.00 | 0.00 to 3.96 |
| Chronic obstructive pulmonary disease | 87 | 1.01 | 0.81 to 1.25 | 17 | 0.43 | 0.25 to 0.69 | 0 | 0.00 | 0.00 to 2.15 | 11 | 1.29 | 0.64 to 2.31 |
| Idiopathic pulmonary fibrosis | 11 | 1.77 | 0.88 to 3.17 | 3 | 1.01 | 0.21 to 2.94 | 1 | 7.40 | 0.19 to 41.2 | 0 | 0.00 | 0.00 to 6.10 |
| Chronic and unspecified nephritis and renal failure | 13 | 0.83 | 0.44 to 1.41 | 6 | 0.85 | 0.31 to 1.85 | 1 | 2.29 | 0.06 to 12.8 | 1 | 0.61 | 0.02 to 3.41 |
Four men and two women of unknown paycode were excluded.
Based on US population rates 1940–2004 for all outcomes except idiopathic pulmonary fibrosis (based on US population rates 1960–2004).
ICD codes were mapped to cause of death categories as described by Robinson and colleagues23 and as described on the NIOSH website (http://www.cdc.gov/niosh/ltas/rates.html).
COPD, chronic obstructive pulmonary disease; FMPC, Feed Materials Production Center; IPF, Idiopathic pulmonary fibrosis; MN, malignant neoplasm; Obs, observed number of deaths; SMR, standardised mortality ratio.