Table 2.
Variable | Univariate analysis | Multivariable analysis† | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Sex | ||||
F vs M | 0.27 (0.07 to 1.01) | .07 | ||
Age, y | ||||
<60 vs ≥ 60 | 0.25 (0.06 to 0.99) | .03 | ||
Clinical stage | ||||
Res vs BR | 0.68 (0.18 to 2.55) | .58 | ||
CES2 | ||||
High vs Int/Low | 0.14 (0.04 to 0.51) | .02 | 0.03 (0.002 to 0.58) | .02 |
Grade | ||||
Mod vs Poor | 0.73 (0.19 to 2.77) | .66 | ||
Chemoradiation Therapy | ||||
Yes vs No | 0.33 (0.05 to 2.15) | .10 | ||
Nodal status | ||||
Pos vs Neg | 2.04 (0.53 to 7.85) | .27 | ||
Tumor size | ||||
<3.3 vs ≥ 3.3 cm | 0.43 (0.08 to 2.38) | .21 | 0.09 (0.008 to 0.85) | .04 |
* Cox proportional hazards models. All statistical tests were two-sided. BR = borderline resectable; CI = confidence interval; HR = hazard ratio; Int = intermediate; Mod = moderate; Neg = negative; Pos = positive; Res = resectable.
† Variables included into the equation after stepwise selection.