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. 2015 May 13;107(8):djv137. doi: 10.1093/jnci/djv137

Figure 1.

Figure 1.

The gene expression (mRNA) level of FGL2 and prognosis in glioblastoma multiforme (GBM) patients. A) Plots showing copy-number analysis of the FGL2 gene in tumors from the low-grade glioma (n = 262) and glioblastoma multiforme (n = 136) databases. These levels are derived from the GISTIC copy-number analysis algorithms and indicate the copy-number level per gene. Chi-square test: P < .001. B) The overall survival rates of GBM patients were stratified by FGL2 gene expression levels. Data on survival of GBM patients and FGL2 mRNA expression data were downloaded and retrieved from the The Cancer Genome Atlas data portal (https://tcga-data.nci.nih.gov/tcga/dataAccessMatrix.htm Accessed May 1, 2015). GBM patients were grouped by FGL2 gene expression level: the 50% of patients top ranked for FGL2 levels were placed in the FGL2High group and the lowest ranked 50% of patients in the FGL2Low group. FGL2 = Fibrinogen-like protein 2.