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. 2015 May 13;107(8):djv137. doi: 10.1093/jnci/djv137

Figure 4.

Figure 4.

Correlation analysis of mRNA expression levels between FGL2 and immune suppressive checkpoints and cytokines in glioblastoma multiforme (GBM) tumors. The Pearson test was used to analyze the correlation between gene expression of the immunosuppressive mediators (programmed death-ligand 1 [PD-L1, A], programmed death-ligand 2 [PD-L2, B], programmed cell death protein 1 [PD-1, C], CD39 [D], B- and T-lymphocyte attenuator [BTLA, E], lymphocyte-activation gene 3 [LAG3, F], cytotoxic T-lymphocyte-associated protein 4 [CTLA-4, G], transforming growth factor-β1 [TGF- β1, H], interleukin-10 [IL-10, I]) and FGL2. mRNA expression data for these genes were downloaded from the GBM database. R = Pearson correlation coefficient.