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. 2015 Aug 23;7(10):731–741. doi: 10.14740/jocmr2256w

Table 3. Early Postoperative Recovery and Effects of Different Types of Intravenous Opioids [7, 10, 18-23, 30].

Studies Drugs Clinical variables Results
Guy et al, 1997 [10] Remifentanil vs. fentanyl ET
Quality of recovery
No statistical difference
Low recovery score within 60 min more in fentanyl group
Naloxone use more in fentanyl group
Citerio et al, 2012 [23] Sevoflurane/remifentanil vs. sevoflurane/fentanyl vs. propofol/remifentanil Aldrete score No statistical difference
Gerlach et al, 2003 [18] Remifentanil/propofol vs. sufentanil IV pushes/propofol ET Remifentanil group had earlier ET 6.4 min vs. 14.3 min (P = 0.003)
Balakrishnan et al, 2000 [19] Remifentanil vs. fentanyl ET (P = 0.04)
Obay commands (P < 0.001)
ET (P = 0.04)
Recovery in 10 min (P = 0.005)
Recovery in 20 min
Better in remifentanil group
No statistical difference
Van der Zwan et al, 2005 [22] Remifentanil/piritramide vs. fentanyl GCS
Aldrete score
No statistical difference
Del Gaudio et al, 2006 [7] Remifentanil vs. fentanyl ET
Obey commands
Orientationx3
Aldrete score
Remifentanil group faster (P < 0.001)
Djian et al, 2006 [20] Remifentanil vs. sufentanil ET No statistical difference
Bilotta et al, 2007 [21] Remifentanil vs. sufentanil ET
SOMCT
No statistical difference
Higher in remifentanil group (P < 0.0001)
From et al, 1990 [30] Alfentanil vs. fentanyl vs. sufentanil Alertness More in alfentanil group

ET: extubation time; GCS: Glasgow coma scale; SOMCT: short orientation memory concentration test.