Table 4. Studies Addressing Postoperative Hemodynamic Recovery [7, 10-14, 16, 17, 19, 20, 24, 30, 38].
Studies | Drugs | Clinical variable | Results |
---|---|---|---|
Lauta et al, 2010 [11] | Sevoflurane/remifentanil vs. propofol/remifentanil | HR MAP |
No statistical difference Sevo/Remi - more hypotension episodes (P = 0.0167) |
Ravussin et al, 1991 [24] | Thiopental/isoflurane vs. propofol | HR, MAP CPP |
No statistical difference Lower in propofol group |
Todd et al, 1993 [12] | Propofol/fentanyl vs. isoflurane/nitrous oxide vs. fentanyl/nitrous oxide | ICP MAP HR |
Iso/N2O - higher ICP, HR, lower MAP The difference is not statistically significant |
Guy et al, 1997 [10] | Remifentanil vs. fentanyl | SBP ICP, CPP |
Higher in fentanyl group P = 0.004 No statistical difference |
Talke et al, 2002 [13] | Propofol vs. isoflurane vs. propofol/isoflurane | BP, HR | No statistical difference |
Magni et al, 2005 [14] | Sevoflurane/fentanyl vs. propofol/remifentanil | MAP: intraoperative hypotension; postoperative HTN HR |
Remifentanil group had more hypotension intraoperative (P = 0.002), hypertension postoperative (P = 0.0046) No statistical difference |
Bhagat et al, 2008 [16] | Propofol vs. fentanyl vs. isoflurane | Less esmolol use with fentanyl P = 0.001 | |
Sneyd et al, 2005 [17] | Remifentanil/propofol vs. remifentanil/sevoflurane | MAP | Remi/Sevo - more hypotension episodes (P = 0.053) |
Balakrishnan et al, 2000 [19] | Remifentanil vs. fentanyl | HR, MAP | No statistical difference |
Del Gaudio et al, 2006 [7] | Remifentanil vs. fentanyl | HR, MAP | No statistical difference |
Djian et al, 2006 [20] | Remifentanil vs. sufentanil | MAP HR |
Remifentanil P = 0.037 better MAP, HR stability |
From et al, 1990 [30] | Alfentanil vs. fentanyl vs. sufentanil | RR PH |
Lower after extubation in Sufentanil group |
Warner, 1996 [38] | Alfentanil vs. remifentanil | ICP MAP decrease |
No statistical difference |