Table 2.

Univariate analyses of the impact of prognostic factors on overall survival (OS) and progression free survival (PFS)

OS			PFS
All patients			All patients
HR (95 % CI)	p-value	Factors	HR (95 % CI)	p-value
0.991 (0.981-1.001)	0.089	Interval surgery → RCT	0.994 (0.985-1.003)	0.188
1.017 (0.985-1.049)	0.303	Radiation treatment time	1.008 (0.978-1.039)	0.616
0.994 (0.985-1.003)	0.198	Overall duration of treatment	0.995 (0.987-1.004)	0.277
1.037 (1.026-1.048)	<0.001	Age	1.025 (1.016-1.035)	<0.001
1.389 (1.062-1.816)	0.016	ECOG state ≤ 1 vs > 1	1.241 (0.957-1.610)	0.104
1.768 (1.397-2.236)	<0.001	RPA-class ≤ 4 vs > 4	1.650 (1.315-2.070)	<0.001
1.825 (1.440-2.314)	<0.001	Resection status (total vs. subtotal)	1.560 (1.248-1.951)	<0.001
0.604 (0.474-0.769)	<0.001	Simultaneous CT	0.669 (0.528-0.848)	0.001
0.888 (0.703-1.122)	0.321	Fractionation	1.002 (0.806-1.246)	0.984
0.312 (0.120-0.813)	0.017	MGMT methylation	0.447 (0.220-0.909)	0.026