Table 3.
BED comparison between standard and explored RT schedule [11]
| RT schedule | BED tumor control α/β 4 | BED acute effects α/β 10 | BED fibrosis α/β 1.7 | BED vascular damage α/β 2.5 | ||||
|---|---|---|---|---|---|---|---|---|
| W.B. = whole breast | W.B. | B.S | W.B. | B.S | W.B. | B.S | W.B. | B.S |
| B.S. = tumor bed side | ||||||||
| 60 Gy/30 F/6 W | 75 | 90 | 60 | 72 | 109 | 131 | 90 | 108 |
| (50 Gy + 10 Gy seq.boost) | ||||||||
| 52 Gy/20/F/5 W (46 Gy + 6 Gy cc.boost) | 72 | 87 | 57 | 66 | 108 | 135 | 88 | 108 |
| UK START TRIAL A | 75 | 75 | 55 | 55 | 120 | 120 | 95 | 95 |
| 41.6 Gy/13 F/5 W | ||||||||
| UK START TRIAL A | 68 | 68 | 51 | 51 | 108 | 108 | 86 | 86 |
| 39 Gy/13 F/5 W | ||||||||
boost concomitant boost, seq.boost sequential boost, F fractions, W weeks