Table 2.

Human synaptic plasticity genes up-regulated in HIV-1 clade B and C Tat treated SK-N-MC (fold up regulation): Out of 84 genes analyzed, only the genes significantly (≥3 fold) up-regulate were shown in this table.

Synaptic Plasticity Genes	HIV-1 Clade B Tat Fold Change	HIV-1 Clade C Tat Fold Change	p< Value
ADCY1	5.47	3.2	<0.01
AKT1	7.29	3.34	<0.001
BDNF	3.47	3.08	NS
CAMK2G	6.22	2.93	<0.01
CEBPB	6.17	−1.02	<0.001
EGR1	2.37	3.81	<0.01
EGR2	3.47	3.29	NS
EGR1	9.82	7.01	<0.01
EGR2	4.88	2.6	<0.001
EGR3	7.65	8.93	<0.05
EGR4	5.88	4.16	<0.06
GABRA5	11.09	−1.71	<0.001
GRIA1	4.04	1.2	<0.002
GRIA3	23.2	13.97	<0.001
GRIN1	8.85	7.56	<0.01
GRIN2B	4.25	1.16	<0.001
GRIN2C	4.81	3.75	<0.05
GRIN2D	3.22	1.26	<0.01
GRM3	24.86	13.07	<0.001
GRM4	8.32	13.91	<0.001
GRM5	3.65	1.67	<0.001
GRM7	3.91	3.38	NS
JUNB	4.52	5.2	NS
KIF17	4.71	−2.35	<0.03
KLF10	4.81	3.75	<0.05
NFKBIB	24.86	13.07	<0.001
NGF	8.32	13.91	<0.001
NGFR	3.65	1.67	<0.01
NOSI	17.91	3.38	<0.001
NR4AI	4.52	5.2	NS
NTF4	4.52	5.2	NS
PMII	11.2	6.53	<0.001
PPP2CA	8.55	11.78	<0.01
PRKCA	3.75	2.69	<0.01
RAB3A	54.8	28.6	<0.001
RELA	3.07	1.88	<0.01
RGS2	2.4	3.63	<0.05
SIRT1	2.78	3.55	NS
SYNPO	5.12	5.81	NS
TNF	6.09	−1.91	<0.001