Fig. 1.

Data from a series of five women who underwent ovarian tissue cryopreservation before the age of 22 years (median 19 years) and before any kind of chemotherapy. Case 1—second orthotopic transplantation at 5 years (still functioning after 11 years), case 2—three pregnancies and deliveries (still functioning after 7 years), case 3—second orthotopic transplantation at 2 years; 1 pregnancy (egg donation) and delivery, case 4—two pregnancies and deliveries (still functioning after 5 years), and case 5—graft still functioning after 5 years