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Confocal microscope images of PBMCs after 24 hours of incubation with BNNS (A1-3), free CpG ODNs (B1-3), CpG ODNs loaded on BNNS (C1-3), CpG ODNs loaded on BNNS–PEI complexes (D1-3).
Note: CpG ODNs were labeled with FITC.
Abbreviations: BNNS, boron nitride nanospheres; DIC, differential interference contrast; FITC, fluorescein isothiocyanate; ODN, oligodeoxynucleotide; PBMCs, peripheral blood mononuclear cells; PEI, polyethyleneimine.
