Table 3.
Prevalence of 20 virulence factors and virulence score of human and animal Escherichia coli B2 commensal strains
| Genes | Description | Human “exclusive” (%) (n = 20) | P value* | Human “non-exclusive” (%) (n = 10) | Animal (%) (n = 13) | P value* |
|---|---|---|---|---|---|---|
| papC | Pilus | 45 | 0.005a | 40 | 0 | 0.004b |
| papGIII | Pilus | 15 | 10 | 0 | ||
| sfa/foc | F1C-fimbriae | 50 | 0.06a | 10 | 15.38 | |
| 0.05c | ||||||
| iha | Iron-regulated-gene-homolog adhesin | 15 | 40 | 0 | ||
| hra | Heat-resistant agglutinin | 35 | 10 | 38.46 | ||
| ibeA | Invasion of brain endothelium | 40 | 40 | 46.15 | ||
| fyuA | Yersiniabactin receptor | 95 | 90 | 84.62 | ||
| irp2 | Yersiniabactin synthesis | 95 | 90 | 84.62 | ||
| iroN | Salmochelin receptor | 80 | 60 | 46.15 | ||
| aer | Aerobactin synthesis | 40 | 20 | 7.69 | ||
| ireA | Iron-responsive element | 20 | 40 | 30.77 | ||
| kpsMTII | Group II capsule antigen | 60 | 70 | 61.54 | ||
| neuC | K1 capsular polysaccharide | 60 | 50 | 23.08 | ||
| ompT | Outer membrane protein | 80 | 90 | 84.62 | ||
| traT | Transfert protein | 50 | 80 | 46.15 | ||
| hlyC | Haemolysin | 35 | 20 | 7.69 | ||
| cnf1 | Cytotoxic necrotizing factor 1 | 30 | 10 | 0 | ||
| usp | Uropathogenic-specific protein | 95 | 0.002a | 100 | 46.15 | <0.001b |
| sat | Secreted autotransporter toxin | 20 | 30 | 0 | ||
| clbQ | Genotoxin colibactin | 60 | 0.01a | 20 | 15.38 | 0.04b |
| 0.05c | ||||||
| VFscore | As in Lefort et al. 2011, calculated on 20 VFs | 10.45 ± 2.52 | 9.40 ± 2.67 | 6.38 ± 2.63 | <0.001b |
VF, virulence factor.
*a
Significant P-value between human “exclusive” and animal isolates
b
Significant P-value between human and animal isolates
c
Significant P-value between human “exclusive” and human “non-exclusive” isolates.