Figure 3. Gene expression by PCR over time of selected genes in NZB/W kidneys.

A. Genes that were upregulated prior to (thick lines) or at (dashed lines) proteinuria onset, reverted during remission and became abnormal again during relapse and were also expressed in human SLE kidney biopsies. B. Genes that were upregulated at proteinuria onset and did not revert during remission. C. Genes that were upregulated at proteinuria onset, reverted at remission and remained normal during late remission.