Table 1.
Individual study characteristics among Caucasians according to primary phenotype (lung cancer)
Stage | Study | Location | Study period | Study design | Case no. | Control no. | Genotyping platform |
---|---|---|---|---|---|---|---|
Discovery (3,953 cases and 4,730 controls) |
Toronto | GTA, Canada | 1997–2002 | Population and Hospital CC | 331 | 499 | Illumina HumanHap300 |
IARC | Central Europe | 1998–2002 | Hospital CC | 1,964 | 2,610 | Illumina HumanHap300 | |
MDACC | Texas, USA | 1997–2007 | Hospital CC | 1,154 | 1,137 | Illumina HumanHap300 | |
HMGU | Germany | 2000–2008 (LUCY) | Population CC | 504 | 484 | Illumina HumanHap550 | |
1990–1998 (KORA) | |||||||
1997–2007 (Heidelberg) | |||||||
Replication (7,510 cases and 7,476 controls) |
NCI (dbGaP) | USA and Italy | 1985–2005 | Population CC | 5,699 | 5,815 | HumanHap550v3.0 |
Human610_Quadv_1_B | |||||||
Human1M_Duov3_b | |||||||
HumanHap300v1.1 | |||||||
HumanHap250Sv1.0 | |||||||
MSH-PMH | Toronto, Canada | 2009–2013 | Clinic CC | 1,073 | 939 | Axiom array | |
MEC | USA | 1993–1996 | Nested CC | 215 | 225 | Axiom array | |
Harvard | USA | 1990–2006 | Nested CC | 523 | 497 | Axiom array |