Table A2.
Characteristics of the 188 Patients Who Experienced Recurrence
| Characteristic | No. | % |
|---|---|---|
| Location | ||
| Locoregional | 59 | 31 |
| Regional lymph nodes | 13 | |
| Same side | 34 | |
| Residual lobe (sublobar resection) | 9 | |
| Staple line | 5 | |
| Distant metastasis | 100 | 53 |
| Single site | 73 | |
| Multisite | 27 | |
| Both (locoregional and distant) | 29 | 15 |
| Intrathoracic only | 102 | 54 |
| Extrathoracic | 86 | 46 |
| Distant metastasis location* | ||
| Bone | 39 | |
| Contralateral lung | 34 | |
| Brain | 29 | |
| Pleural disease | 27 | |
| Distant lymph node | 18 | |
| Adrenal | 13 | |
| Liver | 10 | |
| Chest wall | 7 | |
| Other | 8 | |
| Detection method | ||
| Scheduled computed tomography scan | 123 | 65 |
| Locoregional | 56 | |
| Distant metastasis | 67 | |
| Symptoms | 60 | 32 |
| Locoregional | 2 | |
| Distant metastasis | 58 | |
| Other (carcinoembryonic antigen) | 4 | 2 |
| Unknown | 1 | 1 |
| Initial therapy of recurrence | 157 | 84 |
| Single therapy | 120 | 64 |
| Chemotherapy | 49 | |
| Radiation therapy | 37 | |
| Surgery | 32 | |
| Radiofrequency ablation | 2 | |
| Multimodality therapy | 37 | 20 |
| Chemotherapy + radiation therapy | 17 | |
| Surgery + radiation therapy | 11 | |
| Surgery + chemotherapy | 8 | |
| Surgery + chemotherapy + radiation therapy | 1 | |
| Palliative therapy | 2 | 1 |
| Observation | 5 | 3 |
| Unknown | 24 | 13 |
*
Sites of multiple metastases were counted individually.