Table 1.
Subject demographics (all subjects).
DLB (n = 23) | AD (n = 46) | P-value | |
---|---|---|---|
No. Microbleeds Positive (%) | 7 (30) | 11 (24) | 0.56 |
No. Female (%) | 3 (13) | 13 (28) | 0.16 |
Age at mri yrs. | 69 (64, 74) | 71 (62, 78) | 0.72 |
Age at onset. | 63 (57, 70) | 64 (57, 70) | 0.63 |
Disease duration, yrs. | 6 (4, 10) | 5 (4, 9) | 0.63 |
Education, yrs. | 16 (14, 18) | 16 (14, 17) | 0.90 |
APOE ε carrier, n (%) | 9 (41) | 33 (73) | 0.01 |
CDR-Sum of Boxes score | 6 (4, 8) | 4 (3, 7) | 0.17 |
Dementia Rating Scale. | 124 (104, 130) | 118 (103, 126) | 0.88 |
Whole brain density, mean (sd) | 1.39 (2.47) | 5.51 (17.12) | 0.12 |
Presence of vascular disease and risk factors for vascular disease | |||
Cardiovascular disease (%) | 4 (19) | 8 (19) | >0.99 |
Stroke/TIA (%) | 0 (0) | 1 (2) | >0.99 |
Hypertension (%) | 7 (32) | 25 (54) | 0.08 |
Diabetes (%) | 2 (9) | 1 (2) | 0.55 |
Unless otherwise indicated, values shown are median (IQR). P values were calculated using Student’s t test or chi-squared test as appropriate. Abbreviations: CDR, Clinical Dementia Rating. Disease duration is years from onset date to scan date.