Figure 4.

Evidence for the alternative splicing of exon 37 in zebrafish NCoR2. (a) RT-PCR analysis of RNA taken from a timecourse of zebrafish early development. The 37b− isoform is predominant and the 37b(+) isoform is only detectable in later development. (b) Adult zebrafish were dissected into different parts and extracted RNA assayed by RT-PCR. The 37b+ isoform is only detected in brain and eye suggesting the tissue-specific control of the alternative splicing of this exon. A similar pattern is seen in mice but not frogs [27].