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. 2015 Aug 12;5(8):150082. doi: 10.1098/rsob.150082

Figure 2.

Figure 2.

Recruitment of the polo-like kinases Plk4/ZYG-1 and domain organization of the centriolar receptors. (a) Different recruitment modes of ZYG-1/Plk4 by their respective centriolar receptors SPD-2/Asterless. Caenorhabditis elegans has only one centriolar receptor, SPD-2, to recruit ZYG-1. Drosophila has both SPD-2 and Asterless, but only Asterless can bind and recruit Plk4. In humans, both SPD-2 and Asterless bind Plk4 but in a mutually exclusive manner to temporally and spatially regulate Plk4 recruitment. (b) Domain organization of SPD-2 homologues. Residue numbers of domain boundaries are shown above the schematics. (c) Domain organization of Asterless and Cep152.