Table 5. Binary logistic regression of risk factors associated with presence of mitral annulus calcification (MAC).
| Unadjusted Odds Ratio (O.R.) | (95% C.I.for O.R.) | p-value | Adjusted Odds Ratio (O.R.) | (95% C.I.for O.R.) | p-value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 1.076 | ( | 1.038 | - | 1.115 | ) | <0.0001 | 1.083 | ( | 1.041 | - | 1.128 | ) | <0.0001 |
| Phytate (μM) | 0.599 | ( | 0.387 | - | 0.929 | ) | 0.022 | 0.640 | ( | 0.414 | - | 0.990 | ) | 0.045 |
| Leukocytes (x103/μL) | 1.138 | ( | 1.009 | - | 1.284 | ) | 0.035 | 1.152 | ( | 1.005 | - | 1.320 | ) | 0.042 |
| Phosphorous (mg/dL) | 1.881 | ( | 1.224 | - | 2.892 | ) | 0.004 | 1.970 | ( | 1.199 | - | 3.239 | ) | 0.007 |
| Diabetes (yes vs. no) | 2.178 | ( | 1.127 | - | 4.208 | ) | 0.021 | |||||||
| Hypertension (yes vs. no) | 1.832 | ( | 0.974 | - | 3.445 | ) | 0.060 | |||||||
| Glucose (mg/dL) | 1.009 | ( | 1.000 | - | 1.018 | ) | 0.052 | |||||||
| Total cholesterol (mg/dL) | 1.008 | ( | 0.999 | - | 1.016 | ) | 0.068 | |||||||
| Neutrophil/Lymphocyte ratio | 1.079 | ( | 0.922 | - | 1.262 | ) | 0.342 | |||||||
Statistics: Univariate and multivariate binary logistic regressions were used to identify risk factors associated with presence of MAC. Multivariate analysis was performed using the stepwise backward method.