Table 1.
FMD | HC | p-valuea | |
---|---|---|---|
Number of subjects | 33 | 33 | |
Age | 43.4 ± 11.6 | 41 ± 10.1 | 0.41 |
Sex, female/male | 25/8 | 24/9 | 0.78 |
Females using oral contraception | 4 (16%) | 1 (4%) | 0.18 |
Cigarette smokers | 3 (9%) | 2 (6%) | 0.65 |
History of mood disorder | 15 (45%) | 4 (12%) | 0.002 |
History of anxiety disorder | 21 (64%) | 9 (27%) | 0.002 |
History of post-traumatic stress disorder | 8 (24%) | 4 (12%) | 0.21 |
Taking CNS-acting medicationb | 19 (58%) | 0 | < 0.001 |
Disease duration, years (range) | 4.69 ± 4.97 (0.4 – 19) | - | - |
by 2-tailed student’s t-test;
CNS-acting medications included clonazepam (n=8), lorazepam (n=2), alprazolam (n=1), duloxetine (n=2), gabapentin (n=6), trihexyphenidyl (n=2), carbidopa-levodopa (n=1), ropinirole (n=1), baclofen (n=1), citalopram (n=1), sertraline (n=3), acetazolamide (n=2), desvenlafaxine (n=1), and adderall (n=1).