Table 2.
qPCR data of selected genes for verification in the sciatic nerve of 60-day-old pre-symptomatic SOD1G93A mice.
| Gene symbol | Fold change | p-value |
|---|---|---|
| Ngfr | 1.88 | 0.0051 |
| E2f1 | 1.41 | 0.0353 |
| Traf2 | 1.37 | 0.0150 |
| Erbb3 | 1.29 | 0.0390 |
| Cdkn1a | 1.26 | 0.0297 |
| Foxo3 | −1.96 | 0.0023 |
| Hspa1a | 2.06 | 0.0006 |
| Prdx2 | 1.51 | 0.0359 |
| Mapk10 | 1.35 | 0.0442 |
| Mtor | −1.23 | 0.0443 |
qPCR of differentially expressed genes in sciatic nerves of SOD1G93A mice compared to the wild-type controls selected from microarray data (p < 0.05; see text for details). The genes are related to death, stress and mitochondrion. The means of fold change and p-values are shown, according unpaired two-tailed t-test. The regulation of studied genes for verification showed the same direction as that found in the microarray experiments (Table 3).