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. 2015 Sep 1;6:192. doi: 10.3389/fneur.2015.00192

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Copyright © 2015 Evangelista, Bénar, Bonini, Carron, Colombet, Régis and Bartolomei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Increase of the thalamic synchronization index (Th index) in the ES period compared to the SO period in all seizures analyzed (p < 0.0001 for each comparison) by Wilcoxon test. (B) Negative correlation between global index and seizure duration (p = 0.045) and inverse tendency between Th index and seizure duration (p = 0.052, R² 0.40) in the ES period by Spearman test. (C) Different patterns of the increase of thalamic connectivity between groups A and B in the ES period; pattern A seizures (N_A = 6) showed an overall stable, higher, and longer increase of thalamo-cortical synchronization clearly before the end of seizure compared to pattern B seizures (N_B = 16). The mean and the average deviation of values are shown. Dashed arrow indicates the end of seizure.