Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 1;6:239. doi: 10.3389/fphys.2015.00239

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Debold.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

ROS mediated fatigue and Ca⁺⁺-sensitivity. Force-calcium relation plotted during fatigue of intact mouse flexor brevis muscle fibers stimulated at 100 Hz, at 37°C. Force expressed relative to rested value under control conditions. Fatigue under control conditions produced a strong rightward shift in the relation and depressed maximal force. Maximal force but not Ca⁺⁺-sensitivity was restored with caffeine. Treatment with dithiothreitol (DTT) restored Ca⁺⁺-sensitivity. Reprinted from Moopanar and Allen (2006) with permission from John Wiley and Sons publishing company.