Table 2.
Clinical and epidemiologic characteristics of the population grouped by sex.
| Characteristic | Sex | p | |
|---|---|---|---|
| Females (n = 268) | Males (n = 200) | ||
| Age, year | 56.7 ± 9.4 | 56.7 ± 10.7 | 0.990 |
| Height, cm | 157.6 ± 5.3 | 169.6 ± 5.9 | <0.001 |
| Weight, kg | 64.4 ± 9.5 | 73.3 ± 10.6 | <0.001 |
| Body mass index, kg/m2 | 25.9 ± 3.6 | 25.4 ± 3.1 | 0.115 |
| Systolic blood pressure, mm Hg | 154.6 ± 12.0 | 153.8 ± 11.5 | 0.465 |
| Diastolic blood pressure, mm Hg | 92.0 ± 8.2 | 95.0 ± 8.7 | <0.001 |
| Folate, nmol/L | 13.62 (10.48–16.92) | 11.50 (8.90–13.40) | <0.001 |
| Homocysteine, μmol/L | 11.34 (9.12–14.23) | 15.96 (11.50–19.18) | <0.001 |
| Clinical center | |||
| Ha’rbin | 35 (13.1) | 24 (12.0) | <0.001 |
| Shanghai | 48 (17.9) | 13 (6.5) | |
| Shenyang | 44 (16.4) | 34 (17.0) | |
| Beijing | 67 (25.0) | 47 (23.5) | |
| Xi’an | 30 (11.2) | 47 (23.5) | |
| Nanjing | 44 (16.4) | 35 (17.5) | |
| MTHFR C677T | |||
| CC | 64 (23.9) | 50 (25.0) | 0.880 |
| CT | 139 (51.9) | 99 (49.5) | |
| TT | 65 (24.3) | 51 (25.5) | |
| MTHFR A1298C | |||
| AA | 190 (70.9) | 136 (68.0) | 0.260 |
| AC | 72 (26.9) | 54 (27.0) | |
| CC | 6 (2.2) | 10 (5.0) | |
| MTR A2756G | |||
| AA | 222 (82.8) | 160 (80.0) | 0.367 |
| AG | 45 (16.8) | 37 (18.5) | |
| GG | 1 (0.4) | 3 (1.5) | |
| MTRR A66G | |||
| AA | 77 (28.7) | 76 (38.0) | 0.089 |
| AG | 146 (54.5) | 91 (45.5) | |
| GG | 45 (16.8) | 33 (16.5) | |