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. 2015 Sep 1;5:13699. doi: 10.1038/srep13699

Figure 1. Synthesis of optically and biologically active spirooxindole-type alkaloids by asymmetric strategies.

Figure 1

(A) SPX-F with antipyretic activity, three-step synthesis12; (B) JP-8 g with inflammatory and anti-cancer activities, three-step synthesis13,14; (C) proposed catalytic mechanism for the one-step synthesis of oxindoles in this study; (D) the structure of new oxindole-type molecules.