Figure 4.

Total histone H3 lysine 9 dimethylation (H3K9me2)-associated X-chromosome sequence read count is elevated in fer-1;him-8. Plots represent the H3K9me2 signal on each individual chromosome relative to the average autosomal signal. Plotted data have been corrected for biased input using the BEADS method (Cheung et al. 2011). Each box represents z-scores ranging from the 25th to 75th percentile; line indicates the mean value; whiskers indicate the 2.5th and 97.5th percentiles. Average number of X chromosomal reads is greater and variation is reduced in fer-1;him-8 relative to fer-1 controls.