Table 3.

Dabigatran concentrations and activated partial thromboplastin time (aPTT) according to renal function.

	Total	Creatinine clearance		p Value
	n=316	≥30–<50 mL/min	≥50 mL/min
	n=40 (13%)	n=276 (87%)
Dose of dabigatran, 150 mg×2/day, n (%)	57 (18%)	3 (7.5%)	54 (20%)	0.064
Elapsed time after oral administration (min)	169 (115–300)	143 (109–266)	172 (115–306)	0.35
Plasma concentrations of dabigatran (ng/mL)	89 (41–165)	120 (69–219)	81 (40–152)	0.009
aPTT (s)	38.7 (34.4–44.6)	44.0 (36.2–47.0)	38.3 (34.3–44.5)	0.16

Values are expressed as median and interquartile range, or number (n) and %.