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miR-497 negatively regulated Bcl-2 protein expression at the posttranscriptional level. A. No differences were detected in the levels of Bcl-2 mRNA between miR-497 mimics, inhibitor and negative control cells, P>0.05. B. Cells transfected with miR-497 mimic showed decreased endogenous Bcl-2 protein compared with NC. miR-497 inhibitor showed enhanced Bcl-2 protein expression compared with NC.
