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The effect of BEZ235 on GB9B glioblastoma cells. GB9B cells were exposed to increasing doses of BEZ235 (0.1, 1, 5, 10, 20, 30, 50, 60 and 100 nM) for three days. The cytotoxic effect of the inhibitor was evaluated by MTT assay. (A) Results are expressed as percentage of control. Data are mean and standard error of three separate experiments. Microscopy pictures (B) were taken at initial culture day, 48 h and 72 h after the treatment with 10 nM BEZ235 (Magnification 10 ×).
