Table 2.
Correlation between PKM2/VEGF-C status and clinicopathological features (n=218)
| Parameters | PKM2 | P | VEGF-C | P | PKM2 &. VEGF-C | P | ||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
||||||||
| Low (%) | High (%) | Low (%) | High (%) | L/L (%) | L/H &. H/L (%) | H/H (%) | ||||
| Age (year) | ||||||||||
| <45 | 24 (26) | 31 (25) | 0.866 | 22 (27) | 33 (24) | 0.673 | 15 (35) | 16 (18) | 24 (28) | 0.085 |
| ≥45 | 69 (74) | 94 (75) | 60 (73) | 103 (76) | 28 (65) | 73 (82) | 62 (72) | |||
| Tumor stage | ||||||||||
| T1 (<2 cm) | 32 (35) | 38 (30) | 0.460 | 26 (32) | 44 (33) | 0.940 | 15 (36) | 28 (32) | 27 (31) | 0.876 |
| T2+T3 (≥2 cm) | 59 (65) | 87 (70) | 55 (68) | 91 (67) | 27 (64) | 60 (68) | 59 (69) | |||
| Histological grade | ||||||||||
| I | 14 (15) | 8 (6) | 0.030* | 10 (12) | 12 (9) | 0.198 | 8 (19) | 8 (9) | 6 (7) | 0.018* |
| II | 60 (65) | 76 (61) | 55 (67) | 81 (59) | 26 (60) | 63 (71) | 47 (55) | |||
| III | 19 (20) | 41 (33) | 17 (21) | 43 (32) | 9 (21) | 18 (20) | 33 (38) | |||
| Lymph node stage | ||||||||||
| negative | 53 (57) | 44 (35) | 0.001* | 39 (48) | 61 (45) | 0.697 | 21 (49) | 50 (56) | 26 (30) | 0.002* |
| positive | 40 (43) | 81 (65) | 43 (52) | 75 (55) | 22 (51) | 39 (44) | 60 (70) | |||
| Lymphovascular invasion | ||||||||||
| no | 80 (86) | 91 (73) | 0.054 | 73 (89) | 98 (73) | 0.012* | 39 (91) | 75 (84) | 57 (66) | 0.001* |
| yes | 13 (14) | 33 (27) | 9 (11) | 37 (27) | 4 (9) | 14 (16) | 29 (34) | |||
*
Indicates P<0.05.
L/L: Low/Low; L/H: Low/High; H/L: High/Low; H/H: High/High.