Table 2.
SOX-2 and Oct4 expression according to clinicopathological features of EAC
| Features | N | SOX-2 expression [median; IQR] | P | Oct4 expression [median; IQR] | P |
|---|---|---|---|---|---|
| Histological grade | |||||
| G1 | 18 | 1.00; 2.00 | < 0.001* | 1.00; 2.00 | 0.910 |
| G2 | 25 | 1.00; 3.00 | 1.00; 4.00 | ||
| G3 | 26 | 6.00; 10.00 | 1.00; 3.00 | ||
| FIGO stage | |||||
| IA | 27 | 2.00; 6.00 | 0.484 | 1.00; 2.00 | 0.263 |
| IB | 42 | 1.50; 6.00 | 1.00; 4.00 | ||
| Parity | |||||
| Nulliparous | 10 | 1.00; 3.00 | 0.759 | 0.50; 2.00 | 0.340 |
| Primiparous | 11 | 2.00; 6.00 | 1.00; 3.00 | ||
| Multiparous | 48 | 1.50; 8.00 | 1.00; 4.00 | ||
| Diabetes | |||||
| YES | 24 | 3.00; 9.50 | 0.097 | 1.00; 4.00 | 0.861 |
| NO | 45 | 1.00; 4.00 | 1.00; 4.00 | ||
| Arterial hypertension | |||||
| YES | 37 | 1.00; 6.00 | 0.698 | 1.00; 2.00 | 0.022* |
| NO | 32 | 2.00; 6.00 | 2.00; 3.00 | ||
| Obesity | |||||
| YES | 47 | 1.00; 6.00 | 0.741 | 1.00; 4.00 | 0.388 |
| NO | 22 | 2.50; 6.00 | 1.00; 4.00 |
EAC, endometrial adenocarcinoma; IQR, interquartile range.
*
statistically significent value.