Table 3.
Expression of metabolism-related proteins according to breast cancer subtype
| Parameter | Total (n = 406) (%) | Luminal A (n = 168) (%) | Luminal B (n = 87) (%) | HER-2 (n = 32) (%) | TNBC (n = 119) (%) | P-value |
|---|---|---|---|---|---|---|
| p16 | < 0.001 | |||||
| Negative | 31 (7.6) | 3 (1.8) | 9 (10.3) | 1 (3.1) | 18 (15.1) | |
| Low positive | 212 (52.2) | 102 (60.7) | 37 (42.5) | 18 (56.2) | 55 (46.2) | |
| High positive | 163 (40.1) | 63 (37.5) | 41 (47.1) | 13 (40.6) | 46 (38.7) | |
| Alteration of p16 | 0.018 | |||||
| No | 212 (52.2) | 102 (60.7) | 37 (42.5) | 18 (56.2) | 55 (46.2) | |
| Yes | 194 (47.8) | 66 (39.3) | 50 (57.5) | 14 (43.8) | 64 (53.8) | |
| pRB | < 0.001 | |||||
| Negative | 339 (83.5) | 156 (92.9) | 62 (71.3) | 21 (65.6) | 100 (84.0) | |
| Positive | 67 (16.5) | 12 (7.1) | 25 (28.7) | 11 (34.4) | 19 (16.0) |
TNBC, triple negative breast cancer.