Table 4.
Expression of metabolism-related proteins according to breast cancer subtype
| Parameter | Total (n = 406) (%) | Luminal A (n = 168) (%) | Luminal B (n = 87) (%) | HER-2 (n = 32) (%) | TNBC (n = 119) (%) | P-value |
|---|---|---|---|---|---|---|
| p16/pRB status | < 0.001 | |||||
| p16(+)/pRB(+) | 64 (100.0) | 12 (18.8) | 24 (37.5) | 11 (17.2) | 17 (26.6) | |
| p16(+)/pRB(-) | 311 (100.0) | 153 (49.2) | 54 (17.4) | 20 (6.4) | 84 (27.0) | |
| p16(-)/pRB(+) | 3 (100.0) | 0 (0.0) | 1 (33.3) | 0 (0.0) | 2 (66.7) | |
| p16(-)/pRB(-) | 28 (100.0) | 3 (10.7) | 8 (28.6) | 1 (3.6) | 16 (57.1) | |
| Altered p16/pRB status | < 0.001 | |||||
| Altered p16/pRB(+) | 31 (100.0) | 4 (12.9) | 12 (38.7) | 5 (16.1) | 10 (32.3) | |
| Altered p16/pRB(-) | 163 (100.0) | 62 (38.0) | 38 (23.3) | 9 (5.5) | 54 (33.1) | |
| Non-altered p16/pRB(+) | 36 (100.0) | 8 (22.2) | 13 (36.1) | 6 (16.7) | 9 (25.0) | |
| Non-altered p16/pRB(-) | 176 (100.0) | 94 (53.4) | 24 (13.6) | 12 (6.8) | 46 (26.1) |
TNBC, triple negative breast cancer.