Table 2.
Analysis of the association between expression of Flot-2 protein and clinicopathological features of oral squamous cell carcinoma (OSCC) (n=78)
| Flot-2 | |||
|---|---|---|---|
|
|
|||
| Clinicopathological features (n) | Positive (%) | Negative (%) | P-value |
| Age | |||
| <50 years (n=29) | 21 (72.4) | 8 (27.6) | |
| ≥50 years (n=49) | 37 (75.5) | 12 (24.5) | 0.762 |
| Gender | |||
| Male (n=63) | 49 (77.8) | 14 (22.2) | |
| Female (n=15) | 9 (60.0) | 6 (40.0) | 0.156 |
| Cigarette | |||
| Yes (n=47) | 37 (78.7) | 10 (21.3) | |
| No (n=31) | 21 (67.7) | 10 (32.3) | 0.277 |
| Alcohol | |||
| Yes (n=40) | 34 (85.0) | 6 (15.0) | |
| No (n=38) | 24 (63.2) | 14 (36.8) | 0.027* |
| Areca nut | |||
| Yes (n=33) | 26 (78.8) | 7 (21.2) | |
| No (n=45) | 32 (71.1) | 13 (28.9) | 0.443 |
| Pathological grades | |||
| Well (n=57) | 43 (75.4) | 14 (24.6) | |
| Moderate (n=13) | 9 (69.2) | 4 (30.8) | |
| Poor (n=8) | 6 (75.0) | 2 (25.0) | 0.898 |
| Clinical stages | |||
| StageI-II (n=42) | 31 (73.8) | 11 (26.2) | |
| StageIII-IV (n=36) | 27 (75.0) | 9 (25.0) | 0.904 |
| Lymph node status | |||
| LNM (n=28) | 21 (75.0) | 7 (25.0) | |
| No LNM (n=50) | 37 (74.0) | 13 (26.0) | 0.923 |
| Survival status | |||
| Alive (n=55) | 37 (67.3) | 18 (32.7) | |
| Death (n=23) | 21 (91.3) | 2 (8.7) | 0.027* |
*
Chi-square test, statistically significant difference (P<0.05).
Abbreviations: LNM, lymph node metastasis.