Table 5.
The 19 differentially missense mutated genes in type 1PRCC C vs. type 2 PRCC (P < 0.05)**
| SNP_name | Chr | Alleles | Mutation (s) | Gene |
|---|---|---|---|---|
| exm330459 | 3p12.3 | [C/G] | Missense_H75D | CNTN3 |
| exm318874 | 3p21.2 | [A/G] | Missense_R425C, Missense_R426C | VPRBP |
| exm506256 | 5q35.2 | [A/G] | Missense_A328T, Missense_A328T, Missense_A328T | FGFR4 |
| exm611166 | 7p15.2 | [C/G] | Missense_R132S | HOXA11 |
| exm693941 | 8p12 | [A/G] | Missense_T2181I | TEX15 |
| exm727114 | 8q24.3 | [A/C] | Missense_L361R, Missense_L361R | EEF1D |
| exm919007 | 11q12.3 | [G/C] | Missense_A866P | INTS5 |
| exm940191 | 11q13.4 | [A/G] | Missense_R142Q | DNAJB13 |
| exm976848 | 12p13.3 | [T/C] | Missense_R606Q | VWF |
| exm1185487 | 15q24-q25 | [A/G] | Missense_D1086N, Missense_D1086N | AKAP13 |
| exm1368709 | 17q25 | [A/C] | Missense_H288Q | RFNG |
| exm1277466 | 17p13.3 | [T/C] | Missense_P285S | OR1A1 |
| exm1351674 | 17q25.1 | [T/C] | Missense_T407M | GPR142 |
| exm1352075 | 17q25.1 | [T/G] | Missense_T282K | RAB37 |
| exm1379777 | 18q11.2 | [A/G] | Missense_A152T | TAF4B |
| exm1395964 | 19p13.3 | [T/C] | Missense_A314V, Missense_A227V | MADCAM1 |
| exm1529410 | 20p11.21 | [T/C] | Missense_P297S | GZF1 |
| exm1663015 | Xq28 | [T/C] | Missense_V377A | PNMA3 |
**
Type 1 PRCC C vs. type 2 PRCC; Fisher’s exact test.
Abbreviations: PRCC, Papillary renal cell carcinoma; Chr., chromosome; SNP, single nucleotide polymorphism.