Table 5.

Relationship between E2 variants and HPV16 persistent infection

Nucleotide sequence variation	Amino acid variation	Infection		P
		Transient (n=155)	Persistent (n=94)
G2827A	D25D	27	22	0.254
C3158A	T135K	28	8	0.035*
G3248A	R165Q	28	8	0.035*
T3383C	I210T	14	11	0.504
C3409T	P219S	23	15	0.824
G3448A	E232K	14	12	0.356
T3523C	L257L	14	12	0.356
C3683A	T310K	14	11	0.504
C3786A	D344E	26	10	0.175

Fisher exact test.

^*p<0.05, E2 variants associate with HPV16 persistent infection.