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. 2015 Aug 26;9:4897–4907. doi: 10.2147/DDDT.S85837

Table 1.

Metastatic sites of mice

Group Liver metastasis
(mean ± SD)
Lung metastasis
(mean ± SD)
PF-2341066 5.8±2.2 2.3±1.5
DDP 7.3±1.7 8.8±2.4
Combination 3.5±2.5 3.1±2.6
Control 11.8±2.2 5.3±0.9
P-value 0.03 0.06

Notes: PF-2341066 inhibited lung and liver metastases of mice. Compared with control group, the number of lung and liver metastases was significantly reduce in the combination group.

Abbreviation: DDP, cisplatin.