Table 1.
Group | Liver metastasis (mean ± SD) |
Lung metastasis (mean ± SD) |
---|---|---|
PF-2341066 | 5.8±2.2 | 2.3±1.5 |
DDP | 7.3±1.7 | 8.8±2.4 |
Combination | 3.5±2.5 | 3.1±2.6 |
Control | 11.8±2.2 | 5.3±0.9 |
P-value | 0.03 | 0.06 |
Notes: PF-2341066 inhibited lung and liver metastases of mice. Compared with control group, the number of lung and liver metastases was significantly reduce in the combination group.
Abbreviation: DDP, cisplatin.