Table 1.

Clinical correlation of miR-212 expression in HCC

Clinicopathologic features	Total number of patients, n=86	Number of patients		P
		Low miR-212	High miR-212
Age (years)
<50	27	14	13	0.816
≥50	59	29	30
Sex
Male	69	36	33	0.417
Female	17	7	10
HBV
Absent	30	17	13	0.365
Present	56	26	30
Serum AFP level (ng/mL)
<400	34	11	23	0.008*
≥400	52	32	20
Tumor size (cm)
<5	30	9	21	0.007*
≥5	56	34	22
Number of tumor nodules
1	66	31	35	0.307
≥2	20	12	8
Cirrhosis
Absent	37	20	17	0.514
Present	49	23	26
Venous infiltration
Absent	42	19	23	0.388
Present	44	24	20
Edmondson-Steiner grading
I+II	49	19	30	0.017*
III+IV	37	24	13
TNM tumor stage
I+II	61	25	36	0.009*
III+IV	25	18	7

Note:

^*Statistically significant.

Abbreviations: AFP, alpha fetoprotein; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; miR-212, microRNA 212; TNM, tumor-node-metastasis.