Table 2.

Multivariate Cox regression analysis of 5-year overall and disease-free survival of 86 HCC patients

Variables	Overall survival			Disease-free survival
	HR	95% CI	P	HR	95% CI	P
Serum AFP level	1.701	0.666–4.342	0.267	1.064	0.209–5.421	0.940
Tumor size	1.054	0.999–1.112	0.056	1.067	0.504–2.260	0.865
Edmondson-Steiner grading	2.230	0.937–5.308	0.070	1.971	0.827–4.696	0.126
TNM tumor stage	1.023	1.002–1.044	0.032*	1.055	1.019–1.092	0.003*
miR-212 expression	2.148	1.255–3.677	0.005*	3.547	1.644–7.653	0.001*

Note:

^*Statistically significant.

Abbreviations: AFP, alpha fetoprotein; CI, confidence interval; HCC, hepatocellular carcinoma; HR, hazard ratio; miR-212, microRNA 212; TNM, tumor-node-metastasis.