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. 2015 Aug 26;8:2271–2277. doi: 10.2147/OTT.S85753

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© 2015 Cong et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Regulatory network of pivotal miRNAs in PTC.

Notes: Red-marked miRNAs and genes were upregulated and blue-marked miRNAs and genes were downregulated. Key regulatory network nodes were identified, including many genes, such as AXIN2, BCL2, CCND1, RUNX1, CCNE2, and miRNAs such as miR-424, miR-181a/b/d, miR-20b, miR-195, miR-152, and miR-144. Regulatory networks formed by these key nodes are shown, including the internal relationships among thyroid cancer miRNAs and genes.

Abbreviations: miRNAs, microRNAs; PTC, papillary thyroid carcinoma.