Table 4.

Associations between miRNAs and genes with lymph node metastasis

miRNA/gene	Lymph node metastasis (+)	Lymph node metastasis (−)	P-value
miR-146b	3.09 (2.78–3.16)*	2.97 (2.47–3.14)	0.024
miR-222	2.75 (2.62–2.90)	2.65 (2.41–2.84)	0.000
miR-221	3.31 (3.14–3.41)	3.23 (2.97–3.42)	0.004
miR-181a-1	3.78 (3.68–3.91)	3.72 (3.59–3.88)	0.005
miR-152	2.43 (2.30–2.53)	2.48 (2.31–2.68)	0.005
AXIN2	2.39 (2.19–2.60)	2.47 (2.26–2.67)	0.044
TRAF6	2.14 (2.05–2.22)	2.17 (2.08–2.25)	0.048
BCL2	2.92 (2.73–3.06)	3.03 (2.87–3.06)	0.000
HSP90B1	4.42 (4.31–4.57)	4.47 (4.36–4.67)	0.029
PDGFRA	2.24 (1.93–2.58)	1.98 (1.54–2.39)	0.000
RARA	3.09 (3.03–3.17)	3.04 (2.93–3.12)	0.000
RUNX1	3.15 (2.99–3.31)	3.03 (2.68–3.21)	0.000
MET	4.11 (3.93–4.22)	4.00 (3.57–4.17)	0.000

Note:

^*Original expressing data were log transformed.

Abbreviation: miRNAs, microRNAs.