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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Psychol Med. 2014 Aug 4;45(4):759–770. doi: 10.1017/S0033291714001810

Table 2. Regions showing FA reduction in patients with psychosis.

Index A B C D E
MNI co-ordinates of COG in x, y, z −7, 14, 21 −27, −65, 17 17, −26, 36 23, −63, 29 −17, −39, 39
WM tract labels a Body of the Corpus Callosum Left Posterior Thalamic (optic) Radiation, Forceps Major Body of the Corpus Callosum Right Inferior Fronto-occipital Fasciculus Left Cingulate Gyrus Corona Radiata
Cluster Extent 3212 1585 1428 822 110
FA Mean (SD) CTRLS 0.697 (0.025) 0.649 (0.025) 0.572 (0.032) 0.574 (0.025) 0.506 (0.038)
Mean (SD) SCZ 0.682 (0.025) 0.624 (0.025) 0.555 (0.032) 0.548 (0.025) 0.479 (0.038)
Mean (SD) BPP 0.679 (0.028) 0.627 (0.028) 0.548 (0.028) 0.542 (0.023) 0.481 (0.038)
Diagnosis F = 6.903 * F = 15.970 * F = 5.614 * F = 10.930 * F = 4.649 *
AD Mean (SD) CTRLS 0.150 (0.006) 0.143 (0.006) 0.128 (0.006) 0.129 (0.006) 0.117 (0.006)
Mean (SD) SCZ 0.151 (0.006) 0.141 (0.006) 0.129 (0.006) 0.126 (0.006) 0.118 (0.006)
Mean (SD) BPP 0.151 (0.004) 0.141 (0.004) 0.129 (0.004) 0.126 (0.004) 0.118 (0.004)
Diagnosis F = 0.231 F = 1.800 F = 0.773 F = 2.900 F = 0.474
RD Mean (SD) CTRLS 0.380 (0.006) 0.420 (0.006) 0.460 (0.006) 0.460 (0.006) 0.500 (0.006)
Mean (SD) SCZ 0.410 (0.006) 0.460 (0.006) 0.500 (0.006) 0.500 (0.006) 0.540 (0.006)
Mean (SD) BPP 0.400 (0.004) 0.440 (0.004) 0.490 (0.004) 0.490 (0.004) 0.530 (0.004)
Diagnosis F = 6.070 * F = 6.887 * F = 4.667 * F = 4.373 * F = 3.165 *
MoA Mean (SD) CTRLS 0.885 (0.032) 0.728 (0.051) 0.685 (0.064) 0.594 (0.077) 0.559 (0.115)
Mean (SD) SCZ 0.870 (0.031) 0.685 (0.050) 0.648 (0.063) 0.540 (0.076) 0.495 (0.113)
Mean (SD) BPP 0.873 (0.032) 0.708 (0.051) 0.646 (0.061) 0.539 (0.075) 0.530 (0.117)
Diagnosis F = 3.235 * F = 6.691 * F = 4.644 * F = 7.050 * F = 2.277

All clusters survived FWE corrected p value <0.05.

a

White matter labels are provided in accordance with JHU White Matter Tractography Atlas and the ICBM DTI-81 White Matter Labels Atlas (Mori et al. 2005). Only tracts with >5% probability are included in the labels.

*

Denotes p<0.05 for F tests.