Table 3.
Urinary chemistry changes after intervention in test group versus control group.
| Measure | Test | Control | All | P value |
|---|---|---|---|---|
| n (mean ± SD) | n (mean ± SD) | n (mean ± SD) | ||
| Excretion | ||||
| Osmolality (mOsm/kg) | ||||
| Baseline | 32 (910.7 ± 105.3) | 32 (908.2 ± 113.7) | 64 (909.5 ± 108.7) | |
| Study end | 31 (410.4 ± 130.6) | 31 (827.1 ± 224.2) | 62 (618.7 ± 277.9) | |
| Absolute raw change | 31 (−502.1 ± 164.3) | 31 (−84.8 ± 215.4) | 62 (−293.5 ± 283.5) | |
| Adjusted mean change (SE) | −501.7 ± 32.5 | −85.2 ± 32.5 | <0.001 | |
| Urine specific gravity (g/mL) | ||||
| Baseline | 32 (1.0246 ± 0.0033) | 32 (1.0252 ± 0.0034) | 64 (1.0249 ± 0.0033) | |
| Study end | 31 (1.0115 ± 0.0037) | 31 (1.0231 ± 0.0059) | 62 (1.0173 ± 0.0076) | |
| Absolute raw change | 31 (−0.0131 ± 0.0049) | 31 (−0.0022 ± 0.0063) | 62 (−0.0077 ± 0.0079) | |
| Adjusted mean change (SE) | −0.013 ± 0.0009 | −0.0019 ± 0.0009 | <0.001 |
Values are shown for all subjects randomized and for whom data were available. SD, standard deviation; SE, standard error of the mean.
P value determined by analysis of covariance, adjusted for baseline values (parameter and cigarettes consumption).