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. 2015 Aug 31;10(8):e0136728. doi: 10.1371/journal.pone.0136728

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© 2015 Ahn et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — (A) HBV DNA constructs were transfected into Huh7 cells, which were treated with LMV for 3 days. The intracellular HBV DNA was prepared for Southern blot analysis. A representative result has been shown. (B) The relative replication levels of each HBV mutant (no drug vs LMV treatment) were calculated based on the results of Figs 2C and 3A. (C) The relative replication ability of the HBV mutants treated with LMV were determined by Southern blotting and quantified by Phosphorimager (*, P < 0.05). The relative replication levels of each HBV construct was shown as the mean value of at least three independent experiments.