Table 1.
Summary of reported case records and retrospective/prospective studies
| References | Main organ involvement | Dose | Outcome |
|---|---|---|---|
| Gottenberg et al. [17] | Lymph nodes | 4 × 375 mg/m2 | Good |
| Belkhou et al. [15] | Lymph nodes | 2 × 1 g, every 2 weeks | Good |
| Dasilva et al. [13] | Lymph nodes, including peritoneal | Two infusions, dose not specified | Good |
| Bomprezzi et al. [11] | CNS and skin | 2 × 1 g, every 2 weeks, then 1 g every 6 months for 2 years | Good |
| Lower et al. [14] | Eye; 2 of 4 patients also had significant lung involvement | 2 × 1 g, every 2 weeks, then 375 mg/m2 every 4 or 8 weeks for a minimum of 24 months or 1 g every 4 weeks for 10 months | Three responders of four patients |
| Sawaya et al. [12] | Neuromyelitis optica and lymph nodes | Single 1 g infusion | Good |
| Sweiss et al. [16] | Lung | 2 × 1 g, every 2 weeks | Seven full or partial responders of ten patients |